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Lifespan Analysis of Dystrophic mdx Fast-Twitch Muscle Morphology and Its Impact on Contractile Function

Duchenne muscular dystrophy is caused by the absence of the protein dystrophin from skeletal muscle and is characterized by progressive cycles of necrosis/regeneration. Using the dystrophin deficient mdx mouse model, we studied the morphological and contractile chronology of dystrophic skeletal musc...

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Detalles Bibliográficos
Autores principales: Kiriaev, Leonit, Kueh, Sindy, Morley, John W., North, Kathryn N., Houweling, Peter J., Head, Stewart I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8689589/
https://www.ncbi.nlm.nih.gov/pubmed/34950049
http://dx.doi.org/10.3389/fphys.2021.771499