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Synthesis of Azacarbolines via PhIO(2)-Promoted Intramolecular Oxidative Cyclization of α-Indolylhydrazones

[Image: see text] An unprecedented synthesis of polysubstituted indole-fused pyridazines (azacarbolines) from α-indolylhydrazones under oxidative conditions using a combination of iodylbenzene (PhIO(2)) and trifluoroacetic acid (TFA) has been developed. This transformation is conducted without the n...

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Detalles Bibliográficos
Autores principales:	Corrieri, Matteo, De Crescentini, Lucia, Mantellini, Fabio, Mari, Giacomo, Santeusanio, Stefania, Favi, Gianfranco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2021
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8689645/ https://www.ncbi.nlm.nih.gov/pubmed/34871002 http://dx.doi.org/10.1021/acs.joc.1c02217

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