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Flipping the Switch: Innovations in Inducible Probes for Protein Profiling

[Image: see text] Over the past two decades, activity-based probes have enabled a range of discoveries, including the characterization of new enzymes and drug targets. However, their suitability in some labeling experiments can be limited by nonspecific reactivity, poor membrane permeability, or hig...

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Detalles Bibliográficos
Autores principales: McKenna, Sean M., Fay, Ellen M., McGouran, Joanna F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8689647/
https://www.ncbi.nlm.nih.gov/pubmed/34779621
http://dx.doi.org/10.1021/acschembio.1c00572