Binding Affinity Determines Substrate Specificity and Enables Discovery of Substrates for N-Myristoyltransferases

[Image: see text] Kinetic parameters (k(cat) and K(m)) derived from the Michaelis–Menten equation are widely used to characterize enzymes. k(cat)/K(m) is considered the catalytic efficiency or substrate specificity of an enzyme toward its substrate. N-Myristoyltransferases (NMTs) catalyze the N-term...

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Detalles Bibliográficos
Autores principales: Su, Dan, Kosciuk, Tatsiana, Yang, Min, Price, Ian R., Lin, Hening
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8689648/
https://www.ncbi.nlm.nih.gov/pubmed/34956690
http://dx.doi.org/10.1021/acscatal.1c03330

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8689648/
https://www.ncbi.nlm.nih.gov/pubmed/34956690
http://dx.doi.org/10.1021/acscatal.1c03330

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