Cargando…
Binding Affinity Determines Substrate Specificity and Enables Discovery of Substrates for N-Myristoyltransferases
[Image: see text] Kinetic parameters (k(cat) and K(m)) derived from the Michaelis–Menten equation are widely used to characterize enzymes. k(cat)/K(m) is considered the catalytic efficiency or substrate specificity of an enzyme toward its substrate. N-Myristoyltransferases (NMTs) catalyze the N-term...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2021
|
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8689648/ https://www.ncbi.nlm.nih.gov/pubmed/34956690 http://dx.doi.org/10.1021/acscatal.1c03330 |