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mTEC damage risks immune recovery

Whether autologous hematopoietic stem cell transplantation is free from graft-versus-host disease is controversial. Alawam et al. (2021. J. Exp. Med. https://doi.org/10.1084/jem.20211239) now demonstrate that prolonged damage in thymic medullary epithelial cells causes the failure in self-tolerance...

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Detalles Bibliográficos
Autor principal: Takahama, Yousuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8689664/
https://www.ncbi.nlm.nih.gov/pubmed/34919145
http://dx.doi.org/10.1084/jem.20212326