1266. Melatonin for Renal Protection of Patients Treated with Polymyxin B: A Double Blind Randomized Clinical Trial

BACKGROUND: Polymyxins are one of the last resort treatments for carbapenem resistant gram-negative infections. Nephrotoxicity is its main adverse effect and has been related to oxidative stress mechanisms. Melatonin was associated to reduction in polymyxins nephrotoxicity in animal studies. Our obj...

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Detalles Bibliográficos
Autores principales: Rigatto, Maria Helena, Bergo, Pedro, Baldissera, Giulia, Beck, Eduarda, David, Leonardo, Santoro, Lucas, Falci, Diego Rodrigues, Caumo, Wolnei, Zavascki, Alexandre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Poster Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8689713/
http://dx.doi.org/10.1093/ofid/ofab466.1458

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8689713/
http://dx.doi.org/10.1093/ofid/ofab466.1458

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