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The Emergence of the Spike Furin Cleavage Site in SARS-CoV-2

Compared with other SARS-related coronaviruses (SARSr-CoVs), SARS-CoV-2 possesses a unique furin cleavage site (FCS) in its spike. This has stimulated discussion pertaining to the origin of SARS-CoV-2 because the FCS has been observed to be under strong selective pressure in humans and confers the e...

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Detalles Bibliográficos
Autores principales: Chan, Yujia Alina, Zhan, Shing Hei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8689951/
https://www.ncbi.nlm.nih.gov/pubmed/34788836
http://dx.doi.org/10.1093/molbev/msab327