Dexamethasone is a dose-dependent perpetrator of drug–drug interactions: implications for use in people living with HIV

Global use of dexamethasone in COVID-19 patients has revealed a poor understanding of the drug–drug interaction (DDI) potential of dexamethasone, particularly with antiretroviral agents (ARVs). Dexamethasone is both a substrate and a dose-dependent inducer of cytochrome P450 3A4 (CYP3A4). As many AR...

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Detalles Bibliográficos
Autores principales: Jacobs, Tom G, Marzolini, Catia, Back, David J, Burger, David M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8690014/
https://www.ncbi.nlm.nih.gov/pubmed/34791318
http://dx.doi.org/10.1093/jac/dkab412

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8690014/
https://www.ncbi.nlm.nih.gov/pubmed/34791318
http://dx.doi.org/10.1093/jac/dkab412

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