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Galangin Enhances Anticancer Efficacy of 5-Fluorouracil in Esophageal Cancer Cells and Xenografts Through NLR Family Pyrin Domain Containing 3 (NLRP3) Downregulation

BACKGROUND: Galangin is believed to exert antioxidant effects by inhibition of the NLR family pyrin domain containing 3 (NLRP3) inflammasome, which has been linked to chemotherapy sensitivity in cancers. In this study, we explored the synergistic effect of galangin in combination with the chemothera...

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Detalles Bibliográficos
Autores principales: Zhang, Cong, Luo, Cui-Lian, Shang, Guan-Sheng, Jiang, De-Xiong, Song, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8690210/
https://www.ncbi.nlm.nih.gov/pubmed/34916479
http://dx.doi.org/10.12659/MSM.931630