Cargando…
Galangin Enhances Anticancer Efficacy of 5-Fluorouracil in Esophageal Cancer Cells and Xenografts Through NLR Family Pyrin Domain Containing 3 (NLRP3) Downregulation
BACKGROUND: Galangin is believed to exert antioxidant effects by inhibition of the NLR family pyrin domain containing 3 (NLRP3) inflammasome, which has been linked to chemotherapy sensitivity in cancers. In this study, we explored the synergistic effect of galangin in combination with the chemothera...
Autores principales: | Zhang, Cong, Luo, Cui-Lian, Shang, Guan-Sheng, Jiang, De-Xiong, Song, Qi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Scientific Literature, Inc.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8690210/ https://www.ncbi.nlm.nih.gov/pubmed/34916479 http://dx.doi.org/10.12659/MSM.931630 |
Ejemplares similares
-
Posttranslational Regulation of the NLR Family Pyrin Domain-Containing 3 Inflammasome
por: Shim, Do-Wan, et al.
Publicado: (2018) -
Identification of Mutations in the PYRIN-Containing NLR Genes (NLRP) in Head and Neck Squamous Cell Carcinoma
por: Lei, Yu, et al.
Publicado: (2014) -
The Protein Kinase R Inhibitor C16 Alleviates Sepsis-Induced Acute Kidney Injury Through Modulation of the NF-κB and NLR Family Pyrin Domain-Containing 3 (NLPR3) Pyroptosis Signal Pathways
por: Zhou, Jialu, et al.
Publicado: (2020) -
Pyrin- and CARD-only Proteins as Regulators of NLR Functions
por: Le, Hongnga T., et al.
Publicado: (2013) -
β-hydroxybutyrate impairs monocyte function via the ROS-NLR family pyrin domain-containing three inflammasome (NLRP3) pathway in ketotic cows
por: Dong, Zhihao, et al.
Publicado: (2022)