Super-enhancer switching drives a burst in gene expression at the mitosis-to-meiosis transition

Due to bursts in the expression of thousands of germline-specific genes, the testis has the most diverse and complex transcriptome of all organs. By analyzing the male germline of mice, we demonstrate that the genome-wide reorganization of super-enhancers (SEs) drives bursts in germline gene express...

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Detalles Bibliográficos
Autores principales: Maezawa, So, Sakashita, Akihiko, Yukawa, Masashi, Chen, Xiaoting, Takahashi, Kazuki, Alavattam, Kris G., Nakata, Ippo, Weirauch, Matthew T., Barski, Artem, Namekawa, Satoshi H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8690596/
https://www.ncbi.nlm.nih.gov/pubmed/32895557
http://dx.doi.org/10.1038/s41594-020-0488-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8690596/
https://www.ncbi.nlm.nih.gov/pubmed/32895557
http://dx.doi.org/10.1038/s41594-020-0488-3

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