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Super-enhancer switching drives a burst in gene expression at the mitosis-to-meiosis transition
Due to bursts in the expression of thousands of germline-specific genes, the testis has the most diverse and complex transcriptome of all organs. By analyzing the male germline of mice, we demonstrate that the genome-wide reorganization of super-enhancers (SEs) drives bursts in germline gene express...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8690596/ https://www.ncbi.nlm.nih.gov/pubmed/32895557 http://dx.doi.org/10.1038/s41594-020-0488-3 |