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Prevalence of BRCA1 and BRCA2 pathogenic sequence variants in ovarian cancer patients in the Gulf region: the PREDICT study

BACKGROUND: Patients with pathogenic sequence variants (PSVs) in BRCA1/BRCA2 are at high risk of developing ovarian cancer (OC). However, genetic testing for BRCA1/BRCA2 PSVs is still not a routine practice in the Middle East. With the lack of epidemiological studies in the region, we aim to describ...

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Detalles Bibliográficos
Autores principales: Azribi, Fathi, Abdou, Ehab, Dawoud, Emad, Ashour, Mohamed, Kamal, Amgad, Al Sayed, Mohamed, Burney, Ikram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8690897/
https://www.ncbi.nlm.nih.gov/pubmed/34930165
http://dx.doi.org/10.1186/s12885-021-09094-8