Targeting protumor factor chitinase-3-like-1 secreted by Rab37 vesicles for cancer immunotherapy

Background: Chitinase 3-like-1 (CHI3L1) is a secretion glycoprotein associated with the immunosuppressive tumor microenvironment (TME). The secretory mode of CHI3L1 makes it a promising target for cancer treatment. We have previously reported that Rab37 small GTPase mediates secretion of IL-6 in mac...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Pei-Shan, Yu, Min-Hua, Hou, Ya-Chin, Chang, Chih-Peng, Lin, Shao-Chieh, Kuo, I-Ying, Su, Pei-Chia, Cheng, Hung-Chi, Su, Wu-Chou, Shan, Yan-Shen, Wang, Yi-Ching
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8690922/
https://www.ncbi.nlm.nih.gov/pubmed/34987649
http://dx.doi.org/10.7150/thno.65522

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8690922/
https://www.ncbi.nlm.nih.gov/pubmed/34987649
http://dx.doi.org/10.7150/thno.65522

Ejemplares similares