A novel C-terminal heat shock protein 90 inhibitor that overcomes STAT3-Wnt-β-catenin signaling-mediated drug resistance and adverse effects

Rationale: The heat shock protein (Hsp) system plays important roles in cancer stem cell (CSC) and non-CSC populations. However, limited efficacy due to drug resistance and toxicity are obstacles to clinical use of Hsp90 inhibitors, suggesting the necessity to develop novel Hsp90 inhibitors overcomi...

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Detalles Bibliográficos
Autores principales: Lee, Ho Jin, Min, Hye-Young, Yong, Young-Sik, Ann, Jihyae, Nguyen, Cong Truong, La, Minh Thanh, Hyun, Seung Yeob, Le, Huong Thuy, Kim, Hyewon, Kwon, Hyukjin, Nam, Gibeom, Park, Hyun-Ju, Lee, Jeewoo, Lee, Ho-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8690924/
https://www.ncbi.nlm.nih.gov/pubmed/34987637
http://dx.doi.org/10.7150/thno.63788

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8690924/
https://www.ncbi.nlm.nih.gov/pubmed/34987637
http://dx.doi.org/10.7150/thno.63788

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