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Synthesis of novel indole-isoxazole hybrids and evaluation of their cytotoxic activities on hepatocellular carcinoma cell lines

BACKGROUND: Liver cancer is predicted to be the sixth most diagnosed cancer globally and fourth leading cause of cancer deaths. In this study, a series of indole-3-isoxazole-5-carboxamide derivatives were designed, synthesized, and evaluated for their anticancer activities. The chemical structures o...

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Detalles Bibliográficos
Autores principales: Hawash, Mohammed, Kahraman, Deniz Cansen, Ergun, Sezen Guntekin, Cetin-Atalay, Rengul, Baytas, Sultan Nacak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8691034/
https://www.ncbi.nlm.nih.gov/pubmed/34930409
http://dx.doi.org/10.1186/s13065-021-00793-8