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Corneal epithelial differentiation of human pluripotent stem cells generates ABCB5(+) and ∆Np63α(+) cells with limbal cell characteristics and high wound healing capacity

BACKGROUND: Differentiation of functional limbal stem cells (LSCs) from human pluripotent stem cells (hPSCs) is an important objective which can provide novel treatment solutions for patients suffering from limbal stem cell deficiency (LSCD). Yet, further characterization is needed to better evaluat...

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Detalles Bibliográficos
Autores principales: Vattulainen, Meri, Ilmarinen, Tanja, Viheriälä, Taina, Jokinen, Vilma, Skottman, Heli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8691049/
https://www.ncbi.nlm.nih.gov/pubmed/34930437
http://dx.doi.org/10.1186/s13287-021-02673-3