Adaptive Evolution in TRIF Leads to Discordance between Human and Mouse Innate Immune Signaling

The TIR domain-containing adapter inducing IFN-β (TRIF) protein is an innate immune system protein that mediates the MyD88-independent toll-like receptor response pathway in mice and humans. Previously, we identified positive selection at seven distinct residues in mouse TRIF (mTRIF), as compared wi...

Descripción completa

Detalles Bibliográficos
Autores principales: Hyland, Edel M, Webb, Andrew E, Kennedy, Kathy F, Gerek Ince, Z Nevin, Loscher, Christine E, O’Connell, Mary J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8691055/
https://www.ncbi.nlm.nih.gov/pubmed/34893845
http://dx.doi.org/10.1093/gbe/evab268

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8691055/
https://www.ncbi.nlm.nih.gov/pubmed/34893845
http://dx.doi.org/10.1093/gbe/evab268

Ejemplares similares