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Hypoxic in vitro culture reduces histone lactylation and impairs pre-implantation embryonic development in mice

BACKGROUND: Dynamic changes of histone posttranslational modifications are important contexts of epigenetic reprograming after fertilization in pre-implantation embryos. Recently, lactylation has been reported as a novel epigenetic modification that regulates various cellular processes, but its role...

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Detalles Bibliográficos
Autores principales:	Yang, Wanting, Wang, Peijun, Cao, Pengbo, Wang, Shuang, Yang, Yuxiao, Su, Huimin, Nashun, Buhe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8691063/ https://www.ncbi.nlm.nih.gov/pubmed/34930415 http://dx.doi.org/10.1186/s13072-021-00431-6

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