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A Mathematical Model to Characterize the Role of Light Adaptation in Mammalian Circadian Clock
In response to a light stimulus, the mammalian circadian clock first dramatically increases the expression of Per1 mRNA, and then drops to a baseline even when light persists. This phenomenon is known as light adaptation, which has been experimentally proven to be related to the CRTC1-SIK1 pathway i...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8691188/ https://www.ncbi.nlm.nih.gov/pubmed/34950699 http://dx.doi.org/10.3389/fmolb.2021.681696 |