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A Mathematical Model to Characterize the Role of Light Adaptation in Mammalian Circadian Clock

In response to a light stimulus, the mammalian circadian clock first dramatically increases the expression of Per1 mRNA, and then drops to a baseline even when light persists. This phenomenon is known as light adaptation, which has been experimentally proven to be related to the CRTC1-SIK1 pathway i...

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Detalles Bibliográficos
Autores principales: Shi, Yuzeng, Liu, Yu, Yang, Ling, Yan, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8691188/
https://www.ncbi.nlm.nih.gov/pubmed/34950699
http://dx.doi.org/10.3389/fmolb.2021.681696