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Positive Association Between Location of Melanoma, Ultraviolet Signature, Tumor Mutational Burden, and Response to Anti–PD-1 Therapy

Emerging evidence suggests a correlation between the tumor mutational burden (TMB) and the response to programmed cell death-1 protein (PD-1) monotherapy across multiple cancer types. In skin cancers, as high TMB is mostly because of ultraviolet (UV) exposure, we hypothesized a correlation between t...

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Detalles Bibliográficos
Autores principales: Dousset, Léa, Poizeau, Florence, Robert, Caroline, Mansard, Sandrine, Mortier, Laurent, Caumont, Charline, Routier, Émilie, Dupuy, Alain, Rouanet, Jacques, Battistella, Maxime, Greliak, Anna, Cappellen, David, Galibert, Marie-Dominique, Allayous, Clara, Lespagnol, Alexandra, Gerard, Émilie, Kerneuzet, Inès, Roy, Séverine, Dutriaux, Caroline, Merlio, Jean-Philippe, Vergier, Beatrice, Schrock, Alexa B., Lee, Jessica, Ali, Siraj M., Kammerer-Jacquet, Solène-Florence, Lebbé, Céleste, Beylot-Barry, Marie, Boussemart, Lise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8691497/
https://www.ncbi.nlm.nih.gov/pubmed/34950838
http://dx.doi.org/10.1200/PO.21.00084