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Two-Stage Single-Arm Trials Are Rarely Analyzed Effectively or Reported Adequately

PURPOSE: Two-stage single-arm designs have historically been the most common design used in phase II oncology. They remain a mainstay today, particularly for trials in rare subgroups. Consequently, it is imperative such studies be designed, analyzed, and reported effectively. We comprehensively revi...

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Detalles Bibliográficos
Autores principales: Grayling, Michael J., Mander, Adrian P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8691516/
https://www.ncbi.nlm.nih.gov/pubmed/34950839
http://dx.doi.org/10.1200/PO.21.00276