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Durability of mRNA-1273 vaccine–induced antibodies against SARS-CoV-2 variants

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mutations may diminish vaccine-induced protective immune responses, particularly as antibody titers wane over time. Here, we assess the effect of SARS-CoV-2 variants B.1.1.7 (Alpha), B.1.351 (Beta), P.1 (Gamma), B.1.429 (Epsilon), B.1.526...

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Detalles Bibliográficos
Autores principales: Pegu, Amarendra, O’Connell, Sarah E., Schmidt, Stephen D., O’Dell, Sijy, Talana, Chloe A., Lai, Lilin, Albert, Jim, Anderson, Evan, Bennett, Hamilton, Corbett, Kizzmekia S., Flach, Britta, Jackson, Lisa, Leav, Brett, Ledgerwood, Julie E., Luke, Catherine J., Makowski, Mat, Nason, Martha C., Roberts, Paul C., Roederer, Mario, Rebolledo, Paulina A., Rostad, Christina A., Rouphael, Nadine G., Shi, Wei, Wang, Lingshu, Widge, Alicia T., Yang, Eun Sung, Beigel, John H., Graham, Barney S., Mascola, John R., Suthar, Mehul S., McDermott, Adrian B., Doria-Rose, Nicole A., Arega, Jae, Buchanan, Wendy, Elsafy, Mohammed, Hoang, Binh, Lampley, Rebecca, Kolhekar, Aparna, Koo, Hyung, Luke, Catherine, Makhene, Mamodikoe, Nayak, Seema, Pikaart-Tautges, Rhonda, Russell, Janie, Sindall, Elisa, Kunwar, Pratap, Anderson, Evan J., Bechnak, Amer, Bower, Mary, Camacho-Gonzalez, Andres F., Collins, Matthew, Drobeniuc, Ana, Edara, Venkata Viswanadh, Edupuganti, Srilatha, Floyd, Katharine, Gibson, Theda, Ackerley, Cassie M. Grimsley, Johnson, Brandi, Kamidani, Satoshi, Kao, Carol, Kelley, Colleen, Macenczak, Hollie, McCullough, Michele Paine, Peters, Etza, Phadke, Varun K., Rouphael, Nadine, Scherer, Erin, Sherman, Amy, Stephens, Kathy, Teherani, Mehgan, Traenkner, Jessica, Winston, Juton, Yildirim, Inci, Barr, Lee, Benoit, Joyce, Carste, Barbara, Choe, Joe, Dunstan, Maya, Erolin, Roxanne, ffitch, Jana, Fields, Colin, Jackson, Lisa A., Kiniry, Erika, Lasicka, Susan, Lee, Stella, Nguyen, Matthew, Pimienta, Stephanie, Suyehira, Janice, Witte, Michael, Altaras, Nedim Emil, Carfi, Andrea, Hurley, Marjorie, Pajon, Rolando, Sun, Wellington, Zaks, Tal, Coler, Rhea N., Larsen, Sasha E., Neuzil, Kathleen M., Lindesmith, Lisa C., Martinez, David R., Munt, Jennifer, Mallory, Michael, Edwards, Caitlin, Baric, Ralph S., Berkowitz, Nina M., Boritz, Eli A., Carlton, Kevin, Costner, Pamela, Creanga, Adrian, Douek, Daniel C., Gaudinski, Martin, Gordon, Ingelise, Holman, LaSonji, Leung, Kwanyee, Lin, Bob C., Louder, Mark K., Morabito, Kaitlyn M., Novik, Laura, O’Connell, Sarah, Padilla, Marcelino, Swanson, Phillip A., Zhang, Yi, Chappell, James D., Denison, Mark R., Hughes, Tia, Lu, Xiaotao, Pruijssers, Andrea J., Stevens, Laura J., Posavad, Christine M., Gale, Michael, Menachery, Vineet, Shi, Pei-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8691522/
https://www.ncbi.nlm.nih.gov/pubmed/34385356
http://dx.doi.org/10.1126/science.abj4176