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Hyperosmotic stress induces epithelial-mesenchymal transition through rearrangements of focal adhesions in tubular epithelial cells

Epithelial-mesenchymal transition (EMT) of tubular epithelial cells is a hallmark of renal tubulointerstitial fibrosis and is associated with chronic renal injury as well as acute renal injury. As one of the incidences and risk factors for acute renal injury, increasing the osmolality in the proxima...

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Detalles Bibliográficos
Autores principales: Miyano, Takashi, Suzuki, Atsushi, Sakamoto, Naoya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8691603/
https://www.ncbi.nlm.nih.gov/pubmed/34932568
http://dx.doi.org/10.1371/journal.pone.0261345