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Establishment of a human induced pluripotent stem cell neuronal model for identification of modulators of A53T α-synuclein levels and aggregation

Inhibiting formation or promoting degradation of α-synuclein aggregates are among the therapeutical approaches under investigation as disease-modifying treatment strategies for Parkinson’s disease. To support these developments, several in vitro models based on seeded α-synuclein aggregation have be...

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Detalles Bibliográficos
Autores principales:	Vajhøj, Charlotte, Schmid, Benjamin, Alik, Ania, Melki, Ronald, Fog, Karina, Holst, Bjørn, Stummann, Tina Charlotte
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8691628/ https://www.ncbi.nlm.nih.gov/pubmed/34932569 http://dx.doi.org/10.1371/journal.pone.0261536

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