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Structural Determinants of the Neuronal Glycine Transporter 2 for the Selective Inhibitors ALX1393 and ORG25543

[Image: see text] The neuronal glycine transporter GlyT2 modulates inhibitory glycinergic neurotransmission by controlling the extracellular concentration of synaptic glycine and the supply of neurotransmitter to the presynaptic terminal. Spinal cord glycinergic neurons present in the dorsal horn di...

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Detalles Bibliográficos
Autores principales: Benito-Muñoz, Cristina, Perona, Almudena, Felipe, Raquel, Pérez-Siles, Gonzalo, Núñez, Enrique, Aragón, Carmen, López-Corcuera, Beatriz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8691691/
https://www.ncbi.nlm.nih.gov/pubmed/34003005
http://dx.doi.org/10.1021/acschemneuro.0c00602