Proton transfer pathway in anion channelrhodopsin-1

Anion channelrhodopsin from Guillardia theta (GtACR1) has Asp234 (3.2 Å) and Glu68 (5.3 Å) near the protonated Schiff base. Here, we investigate mutant GtACR1s (e.g., E68Q/D234N) expressed in HEK293 cells. The influence of the acidic residues on the absorption wavelengths was also analyzed using a q...

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Detalles Bibliográficos
Autores principales: Tsujimura, Masaki, Kojima, Keiichi, Kawanishi, Shiho, Sudo, Yuki, Ishikita, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8691836/
https://www.ncbi.nlm.nih.gov/pubmed/34930528
http://dx.doi.org/10.7554/eLife.72264

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8691836/
https://www.ncbi.nlm.nih.gov/pubmed/34930528
http://dx.doi.org/10.7554/eLife.72264

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