miR-138 Reduces the Dysfunction of T Follicular Helper Cells in Osteosarcoma via the PI3K/Akt/mTOR Pathway by Targeting PDK1

OBJECTIVE: To study the effect of miR-138 on the function of osteosarcoma (OS) T follicular helper cells (Tfh cells) and its mechanism. METHODS: Peripheral blood mononuclear cells (PBMCs) were isolated from patients with osteosarcoma (OS group) and healthy volunteers (control group). CD4+CXCR5+ Tfh...

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Detalles Bibliográficos
Autores principales: Jiang, Baoen, Kang, Xiuqin, Zhao, Gang, Lu, Jianshu, Wang, Zhitao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8691981/
https://www.ncbi.nlm.nih.gov/pubmed/34950224
http://dx.doi.org/10.1155/2021/2895893

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8691981/
https://www.ncbi.nlm.nih.gov/pubmed/34950224
http://dx.doi.org/10.1155/2021/2895893

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