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Curcumin Relieves Chronic Unpredictable Mild Stress-Induced Depression-Like Behavior through the PGC-1α/FNDC5/BDNF Pathway

METHODS: All rats were randomly divided into four groups, namely, control, CUMS, CUMS + CUR, and CUMS + CUR + SR18292 (PGC-1α inhibitor). Behavioral tests were conducted to assess the antidepressant-like effects of CUR. The expressions of PGC-1α, estrogen-related receptor alpha (ERRα), FNDC5, and BD...

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Detalles Bibliográficos
Autores principales: Wu, Yanqin, Sun, Fusheng, Guo, Yujin, Zhang, Yumao, Li, Li, Dang, Ruili, Jiang, Pei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8692045/
https://www.ncbi.nlm.nih.gov/pubmed/34950248
http://dx.doi.org/10.1155/2021/2630445