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SARS-CoV-2 reactive and neutralizing antibodies discovered by single-cell sequencing of plasma cells and mammalian display

Characterization of COVID-19 antibodies has largely focused on memory B cells; however, it is the antibody-secreting plasma cells that are directly responsible for the production of serum antibodies, which play a critical role in resolving SARS-CoV-2 infection. Little is known about the specificity...

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Detalles Bibliográficos
Autores principales: Ehling, Roy A., Weber, Cédric R., Mason, Derek M., Friedensohn, Simon, Wagner, Bastian, Bieberich, Florian, Kapetanovic, Edo, Vazquez-Lombardi, Rodrigo, Di Roberto, Raphaël B., Hong, Kai-Lin, Wagner, Camille, Pataia, Michele, Overath, Max D., Sheward, Daniel J., Murrell, Ben, Yermanos, Alexander, Cuny, Andreas P., Savic, Miodrag, Rudolf, Fabian, Reddy, Sai T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8692065/
https://www.ncbi.nlm.nih.gov/pubmed/34998467
http://dx.doi.org/10.1016/j.celrep.2021.110242