7,8-Dihydroxyflavone alleviates apoptosis and inflammation induced by retinal ischemia-reperfusion injury via activating TrkB/Akt/NF-kB signaling pathway

Retinal ischemia-reperfusion injury (RIRI) is of common occurrence in retinal and optic nerve diseases. The BDNF/TrkB signaling pathway has been examined to be neuroprotective in RIRI. In this study, we investigated the role of a potent selective TrkB agonist 7,8-dihydroxyfavone (DHF) in rat retinas...

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Detalles Bibliográficos
Autores principales: Yu, Aihua, Wang, Shun, Xing, Yiqiao, Han, Mengyao, Shao, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8692126/
https://www.ncbi.nlm.nih.gov/pubmed/34975295
http://dx.doi.org/10.7150/ijms.65733

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8692126/
https://www.ncbi.nlm.nih.gov/pubmed/34975295
http://dx.doi.org/10.7150/ijms.65733

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