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Engineering of human mesenchymal stem cells resistant to multiple natural killer subtypes

Mesenchymal stem cells (MSCs) as a therapeutic promise are often quickly cleared by innate immune cells of the host including natural killer (NK) cells. Efforts have been made to generate immune-escaping human embryonic stem cells (hESCs) where T cell immunity is evaded by defecting β-2-microglobuli...

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Detalles Bibliográficos
Autores principales: Zheng, Dejin, Wang, Xiaoyan, Zhang, Zhenwu, Li, Enqin, Yeung, Cheungkwan, Borkar, Roma, Qin, Guihui, Wu, Yaojiong, Xu, Ren-He
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8692142/
https://www.ncbi.nlm.nih.gov/pubmed/34975342
http://dx.doi.org/10.7150/ijbs.64640