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MiR-206 suppresses the deterioration of intrahepatic cholangiocarcinoma and promotes sensitivity to chemotherapy by inhibiting interactions with stromal CAFs

Background: Intrahepatic cholangiocarcinoma (iCCA) is a highly malignant subtype of cholangiocarcinoma (CCA) with poor prognosis. In iCCA, the interplay between the stroma and tumor cells results in resistance to adjuvant chemotherapy. Increasing evidence indicates that miR-206 participates in tumor...

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Detalles Bibliográficos
Autores principales: Yang, Renjie, Wang, Dong, Han, Shen, Gu, Yichao, Li, Zhi, Deng, Lei, Yin, Aihong, Gao, Yun, Li, Xiangcheng, Yu, Yue, Wang, Xuehao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8692143/
https://www.ncbi.nlm.nih.gov/pubmed/34975317
http://dx.doi.org/10.7150/ijbs.62602