CD99 antibody disrupts T-cell acute lymphoblastic leukemia adhesion to meningeal cells and attenuates chemoresistance

Central nervous system (CNS) relapse is a significant cause of treatment failure among patients with acute lymphoblastic leukemia. In prior work we found that the meninges, the thin layer of tissue that covers the brain and spinal cord, harbor leukemia cells in the CNS. Importantly, direct interacti...

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Detalles Bibliográficos
Autores principales: Ebadi, Maryam, Jonart, Leslie M., Ostergaard, Jason, Gordon, Peter M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8692434/
https://www.ncbi.nlm.nih.gov/pubmed/34934147
http://dx.doi.org/10.1038/s41598-021-03929-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8692434/
https://www.ncbi.nlm.nih.gov/pubmed/34934147
http://dx.doi.org/10.1038/s41598-021-03929-x

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