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Rats exhibit age-related mosaic loss of chromosome Y

Mosaic loss of the Y chromosome (LOY) is the most frequent chromosomal aberration in aging men and is strongly correlated with mortality and disease. To date, studies of LOY have only been performed in humans, and so it is unclear whether LOY is a natural consequence of our relatively long lifespan...

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Detalles Bibliográficos
Autores principales: Orta, Alberto H., Bush, Stephen J., Gutiérrez-Mariscal, Mariana, Castro-Obregón, Susana, Jaimes-Hoy, Lorraine, Grande, Ricardo, Vázquez, Gloria, Gorostieta-Salas, Elisa, Martínez-Pacheco, Mónica, Díaz-Barba, Karina, Cornejo-Páramo, Paola, Sanchez-Flores, Alejandro, Székely, Tamas, Urrutia, Araxi O., Cortez, Diego
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8692441/
https://www.ncbi.nlm.nih.gov/pubmed/34934158
http://dx.doi.org/10.1038/s42003-021-02936-y