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Rats exhibit age-related mosaic loss of chromosome Y
Mosaic loss of the Y chromosome (LOY) is the most frequent chromosomal aberration in aging men and is strongly correlated with mortality and disease. To date, studies of LOY have only been performed in humans, and so it is unclear whether LOY is a natural consequence of our relatively long lifespan...
Autores principales: | Orta, Alberto H., Bush, Stephen J., Gutiérrez-Mariscal, Mariana, Castro-Obregón, Susana, Jaimes-Hoy, Lorraine, Grande, Ricardo, Vázquez, Gloria, Gorostieta-Salas, Elisa, Martínez-Pacheco, Mónica, Díaz-Barba, Karina, Cornejo-Páramo, Paola, Sanchez-Flores, Alejandro, Székely, Tamas, Urrutia, Araxi O., Cortez, Diego |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8692441/ https://www.ncbi.nlm.nih.gov/pubmed/34934158 http://dx.doi.org/10.1038/s42003-021-02936-y |
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