Short term but highly efficient Cas9 expression mediated by excisional system using adenovirus vector and Cre

Genome editing techniques such as CRISPR/Cas9 have both become common gene engineering technologies and have been applied to gene therapy. However, the problems of increasing the efficiency of genome editing and reducing off-target effects that induce double-stranded breaks at unexpected sites in th...

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Detalles Bibliográficos
Autores principales: Nagamoto, Sayaka, Agawa, Miyuki, Tsuchitani, Emi, Akimoto, Kazunori, Matsushima, Saki Kondo, Kanegae, Yumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8692473/
https://www.ncbi.nlm.nih.gov/pubmed/34934130
http://dx.doi.org/10.1038/s41598-021-03803-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8692473/
https://www.ncbi.nlm.nih.gov/pubmed/34934130
http://dx.doi.org/10.1038/s41598-021-03803-w

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