Cargando…
Short term but highly efficient Cas9 expression mediated by excisional system using adenovirus vector and Cre
Genome editing techniques such as CRISPR/Cas9 have both become common gene engineering technologies and have been applied to gene therapy. However, the problems of increasing the efficiency of genome editing and reducing off-target effects that induce double-stranded breaks at unexpected sites in th...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8692473/ https://www.ncbi.nlm.nih.gov/pubmed/34934130 http://dx.doi.org/10.1038/s41598-021-03803-w |