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Cerebellin-2 Regulates a Serotonergic Dorsal Raphe Circuit that Controls Compulsive Behaviors

Cerebellin-1 (Cbln1) and cerebellin-2 (Cbln2) are secreted glycoproteins that are expressed in distinct subsets of neurons throughout the brain. Cbln1 and Cbln2 simultaneously bind to presynaptic neurexins and postsynaptic GluD1 and GluD2, thereby forming trans-synaptic adhesion complexes. Genetic a...

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Detalles Bibliográficos
Autores principales: Seigneur, Erica, Wang, Jie, Dai, Jinye, Polepalli, Jai, Südhof, Thomas C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8692491/
https://www.ncbi.nlm.nih.gov/pubmed/34158618
http://dx.doi.org/10.1038/s41380-021-01187-x