Controlled rate slow freezing with lyoprotective agent to retain the integrity of lipid nanovesicles during lyophilization

We designed a novel lyophilization method using controlled rate slow freezing (CSF) with lyoprotective agent (LPA) to achieve intact lipid nanovesicles after lyophilization. During the freezing step, LPA prevented water supercooling, and the freezing rate was controlled by CSF. Regulating the freezi...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Eunhye, Yu, Hyunjong, Choi, SungHak, Park, Kyung-Min, Jung, Ho-Sup, Chang, Pahn-Shick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8692592/
https://www.ncbi.nlm.nih.gov/pubmed/34934167
http://dx.doi.org/10.1038/s41598-021-03841-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8692592/
https://www.ncbi.nlm.nih.gov/pubmed/34934167
http://dx.doi.org/10.1038/s41598-021-03841-4

Ejemplares similares