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Long noncoding RNA Meg3 sponges miR-708 to inhibit intestinal tumorigenesis via SOCS3-repressed cancer stem cells growth

BACKGROUND: Colorectal cancer (CRC) remains the most common gastrointestinal cancer and a leading cause of cancer deaths worldwide, with most showing pathologies indicating the malignant transformation of early stage intestinal stem cells. The long non-coding RNA Meg3, which functions as a tumor sup...

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Detalles Bibliográficos
Autores principales: Zhang, Shuo, Ji, Wei-Wei, Wei, Wei, Zhan, Li-Xing, Huang, Xuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8692598/
https://www.ncbi.nlm.nih.gov/pubmed/34934045
http://dx.doi.org/10.1038/s41419-021-04470-5