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Long noncoding RNA Meg3 sponges miR-708 to inhibit intestinal tumorigenesis via SOCS3-repressed cancer stem cells growth
BACKGROUND: Colorectal cancer (CRC) remains the most common gastrointestinal cancer and a leading cause of cancer deaths worldwide, with most showing pathologies indicating the malignant transformation of early stage intestinal stem cells. The long non-coding RNA Meg3, which functions as a tumor sup...
Autores principales: | Zhang, Shuo, Ji, Wei-Wei, Wei, Wei, Zhan, Li-Xing, Huang, Xuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8692598/ https://www.ncbi.nlm.nih.gov/pubmed/34934045 http://dx.doi.org/10.1038/s41419-021-04470-5 |
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