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Clinical strategies to manage adult glioblastoma patients without MGMT hypermethylation

Glioblastoma (GBM) is a highly malignant brain tumor with a dismal prognosis. Standard therapy for GBM comprises surgical resection, followed by radiotherapy plus concomitant and adjuvant temozolomide (TMZ) therapy. The methylation status of the O6-methylguanine DNA methyltransferase (MGMT) promoter...

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Detalles Bibliográficos
Autores principales: Liu, Delin, Yang, Tianrui, Ma, Wenbin, Wang, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8692679/
https://www.ncbi.nlm.nih.gov/pubmed/34976195
http://dx.doi.org/10.7150/jca.63595