HIF1α/HIF2α induces glioma cell dedifferentiation into cancer stem cells through Sox2 under hypoxic conditions

Objective: Our previous study showed that glioma stem-like cells could be induced to undergo dedifferentiation under hypoxic conditions, but the mechanism requires further study. HIF1α and HIF2α are the main molecules involved in the response to hypoxia, and Sox2, as a retroelement, plays an importa...

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Detalles Bibliográficos
Autores principales: Wang, Pan, Gong, Sheng, Liao, Bin, Pan, Jinyu, Wang, Junwei, Zou, Dewei, Zhao, Lu, Xiong, Shuanglong, Deng, Yangmin, Yan, Qian, Wu, Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8692689/
https://www.ncbi.nlm.nih.gov/pubmed/34976166
http://dx.doi.org/10.7150/jca.54402

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8692689/
https://www.ncbi.nlm.nih.gov/pubmed/34976166
http://dx.doi.org/10.7150/jca.54402

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