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Somatic mutation and expression of BAP1 in hepatocellular carcinoma: an indicator for ferroptosis and immune checkpoint inhibitor therapies

BRCA1-Associated Protein 1 (BAP1) is a deubiquitylase that is found associated with multiprotein complexes that regulate key cellular pathways, and subsequent researches have revealed that BAP1 acts independently as a tumor suppressor. Somatic BAP1 mutations occur in various malignancies, but malign...

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Detalles Bibliográficos
Autores principales: Yan, Yu-Chuan, Meng, Guang-Xiao, Ding, Zi-Niu, Liu, Yan-Feng, Chen, Zhi-Qiang, Yan, Lun-Jie, yang, Ya-Fei, Liu, Hui, Yang, Chun-Cheng, Dong, Zhao-Ru, Hong, Jian-Guo, Li, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8692694/
https://www.ncbi.nlm.nih.gov/pubmed/34976173
http://dx.doi.org/10.7150/jca.65574