The Na(+)/Ca(2+) Exchanger 3 Is Functionally Coupled With the Na(V)1.6 Voltage-Gated Channel and Promotes an Endoplasmic Reticulum Ca(2+) Refilling in a Transgenic Model of Alzheimer’s Disease

The remodelling of neuronal ionic homeostasis by altered channels and transporters is a critical feature of the Alzheimer’s disease (AD) pathogenesis. Different reports converge on the concept that the Na(+)/Ca(2+) exchanger (NCX), as one of the main regulators of Na(+) and Ca(2+) concentrations and...

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Detalles Bibliográficos
Autores principales: Piccialli, Ilaria, Ciccone, Roselia, Secondo, Agnese, Boscia, Francesca, Tedeschi, Valentina, de Rosa, Valeria, Cepparulo, Pasquale, Annunziato, Lucio, Pannaccione, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8692738/
https://www.ncbi.nlm.nih.gov/pubmed/34955845
http://dx.doi.org/10.3389/fphar.2021.775271

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8692738/
https://www.ncbi.nlm.nih.gov/pubmed/34955845
http://dx.doi.org/10.3389/fphar.2021.775271

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