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The onset of circulation triggers a metabolic switch required for endothelial to hematopoietic transition

Hematopoietic stem cells (HSCs) emerge during development from the vascular wall of the main embryonic arteries. The onset of circulation triggers several processes that provide critical external factors for HSC generation. Nevertheless, it is not fully understood how and when the onset of circulati...

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Detalles Bibliográficos
Autores principales: Azzoni, Emanuele, Frontera, Vincent, Anselmi, Giorgio, Rode, Christina, James, Chela, Deltcheva, Elitza M., Demian, Atanasiu S., Brown, John, Barone, Cristiana, Patelli, Arianna, Harman, Joe R., Nicholls, Matthew, Conway, Simon J., Morrissey, Edward, Jacobsen, Sten Eirik W., Sparrow, Duncan B., Harris, Adrian L., Enver, Tariq, de Bruijn, Marella F.T.R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8692754/
https://www.ncbi.nlm.nih.gov/pubmed/34910918
http://dx.doi.org/10.1016/j.celrep.2021.110103