Comprehensive Analysis of Chemical Structures That Have Been Tested as CFTR Activating Substances in a Publicly Available Database CandActCFTR

Background: Cystic fibrosis (CF) is a genetic disease caused by mutations in CFTR, which encodes a chloride and bicarbonate transporter expressed in exocrine epithelia throughout the body. Recently, some therapeutics became available that directly target dysfunctional CFTR, yet research for more eff...

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Detalles Bibliográficos
Autores principales: Nietert, Manuel Manfred, Vinhoven, Liza, Auer, Florian, Hafkemeyer, Sylvia, Stanke, Frauke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8692862/
https://www.ncbi.nlm.nih.gov/pubmed/34955819
http://dx.doi.org/10.3389/fphar.2021.689205

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8692862/
https://www.ncbi.nlm.nih.gov/pubmed/34955819
http://dx.doi.org/10.3389/fphar.2021.689205

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