Enhanced Oxygen Utilization Efficiency With Concomitant Activation of AMPK-TBC1D1 Signaling Nexus in Cyclophilin-D Conditional Knockout Mice

We have previously reported in HEK 293 T cells and in constitutive cyclophilin-D (Cyp-D) knockout (KO) mice that Cyp-D ablation downregulates oxygen consumption (VO(2)) and triggers an adaptive response that manifest in higher exercise endurance with less VO(2). This adaptive response involves a met...

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Detalles Bibliográficos
Autores principales: Radhakrishnan, Jeejabai, Baetiong, Alvin, Gazmuri, Raúl J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8692870/
https://www.ncbi.nlm.nih.gov/pubmed/34955879
http://dx.doi.org/10.3389/fphys.2021.756659

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8692870/
https://www.ncbi.nlm.nih.gov/pubmed/34955879
http://dx.doi.org/10.3389/fphys.2021.756659

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